1. Overview
In pharmaceutical R&D and small-batch production, equipment
often faces the issue of mismatched functionality—either
overengineered (causing resource waste) or lacking precision
(compromising data reliability and product quality). The JANGLI
JL-100II Softgel Encapsulation Machine is developed to address this
problem. It complies with GMP, FDA, and CE standards, and is specifically designed for lab-scale R&D and
small-batch production, providing efficient and accurate softgel
preparation solutions for pharmaceutical teams and enterprises.
2. Brand Background & Compliance
JANGLI has over 10 years of experience in refining pharmaceutical
and packaging equipment. The design of the JL-100II integrates the
core principles of "compliance, precision, and practicality," which
are not promotional slogans but practical guidelines. Its
compliance with GMP, FDA, and CE standards serves as a safeguard to
reduce audit pressure and compliance difficulties for R&D teams
in daily operations. The machine’s reliability is verified by
repeated purchases from multiple pharmaceutical laboratories and
research institutions, confirming its applicability in real
pharmaceutical scenarios.
3. Core Advantages
3.1 Scenario Adaptability
The JL-100II is an upgraded lab-grade version of the classic
vertical softgel machine, capable of covering three key scenarios:
small-scale formula testing for new softgels, pilot production for
process validation before industrialization, and small-batch
commercial production for regional supply or market trials. It acts
as a bridge between lab benchwork and industrial pilot production.
With compact dimensions (1440×660×1350mm, H), it fits in limited
lab or small workshop spaces without requiring extensive workspace
rearrangement.
3.2 Performance & Configuration
• Control System: Equipped with a PLC touchscreen for intuitive operation and
flexible parameter adjustment, reducing operator training time.
• Material Selection: Outer shell made of SS304 stainless steel; all fill-contact
components (e.g., plungers, fluid channels) made of 316L stainless
steel, meeting pharmaceutical hygiene standards, resisting
corrosion, and suitable for plant-based vegetarian gelatin
softgels.
• Key Specifications:
Output | 8# Oval (500mg) hits 15,840 capsules/hour; 20# Oblong (1000mg) hits 8,160 capsules/hour |
Die Roller Size | φ80×100mm (4") |
Rotating Speed | 0-5 RPM (frequency-controlled) |
Single Plunger Filling Volume | 0-1.5ml |
Plunger Quantity | 6 total (3 on each side) |
Filling Accuracy | ±0.5% |
Power Consumption | 5kW |
Dimensions | 1440×660×1350 (H) mm |
Weight | 400kgs |
3.3 Gel Box (Pharmaceutical-Grade Tinned Brass)
As a core component in direct contact with gelatin, the gel box
adopts pharmaceutical-grade tinned brass, outperforming resin and
ordinary stainless steel in the following aspects:
• Compliance & Safety: Meets FDA 21 CFR Part 175; tin coating forms an inert barrier,
preventing brass ion leaching and chemical reactions with gelatin,
ensuring formula purity.
• Temperature Control: Brass has high thermal conductivity (~108 W/(m·K)), enabling
uniform heat distribution; paired with a PLC-linked temperature
module, it achieves ±1℃ control accuracy, maintaining gelatin at
50–60℃ (optimal viscosity range) to avoid lumping or brittleness.
Hygiene & Durability: Smooth, pore-free surface prevents residue buildup; cleanable via
built-in CIP system without disassembly; tarnish-resistant,
ensuring long-term compliance and low maintenance costs.
3.4 Structural Design
• Machine Head: Precision-machined core forming component, ensuring consistent
softgel formation and high productivity/accuracy.
• Die Roller Housing: Compact and adjustable, synchronized with the PLC system to
maintain stable die roller operation, enabling operator control
over the forming process.
Gel Box Integration: Mounted on the machine side, connected to the head via a short
food-grade tube; brass’s thermal retention maintains stable gelatin
temperature during transfer, preserving gel film quality.
4. Practical Value
4.1 For R&D Teams
Accelerates small-scale testing and pilot production. The brass gel
box’s precise temperature control and non-reactive surface ensure
data reliability; GMP compliance allows pilot samples to directly
enter filing and verification, shortening the R&D cycle.
4.2 For Small-Batch Producers
Enables market trials or regional supply without investing in
underutilized large equipment. Its cost-effectiveness, space-saving
design, and support for quick formula switches enhance operational
agility.
4.3 Application Case
A pharmaceutical R&D team used the JL-100II to develop a
sustained-release softgel. Within 2 weeks, it completed 3 rounds of
formula adjustments (5,000 samples/round), maintaining ±0.4%
filling accuracy (exceeding the ±0.5% standard) and over 99.5%
softgel integrity, significantly shortening the product approval
timeline.
5. Conclusion
The JANGLI JL-100II is a specialized tool for pharmaceutical lab
R&D and small-batch production, with compliance as the
foundation, precision as the core, and the tinned brass gel box
ensuring gelatin purity and stable performance. It addresses the
inefficiencies of overengineered or imprecise equipment, serving as
a reliable link between lab research and market launch.
